Article
Association of polymorphisms in base excision repair genes with the risk of breast cancer: a case-control study in North Indian women.
Oncology research - 1 Jan 2008
Mitra Amit Kumar, Singh Neetu, Singh Ashok, Garg Vivek Kumar, Agarwal Amit, Sharma Mandira, Chaturvedi Rashmi, Rath Srikanta Kumar
Abstract excerpt
Inheritance of common genetic variants at one or more base excision repair (BER) genes may result in a reduced DNA repair capacity and in an increased risk of cancers like breast cancer. The present case-control study with 390 north Indian women (155 breast cancer cases and 235 controls) was aimed to investigate the association of seven nonsynonymous BER gene polymorphisms viz. rs1130409/T1865G (APEX1),...
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