Article
Transforming growth factor β1 genotypes in relation to TGFβ1, interleukin-8, and tumor necrosis factor alpha in induced sputum and blood in cystic fibrosis.
Mediators of inflammation - 1 Jan 2013
Eickmeier O, Boom L v D, Schreiner F, Lentze M J, NGampolo D, Schubert R, Zielen S, Schmitt-Grohé S
Abstract excerpt
BACKGROUND: High-producer TGFβ1 genotypes are associated with severe lung disease in cystic fibrosis (CF), but studies combining IL-8, TNFα-, and TGFβ1(+genotype) levels and their impact on CF lung disease are scarce. AIM: Assessing the relationship between TGF β 1, IL-8, and TNF- α and lung disease in CF in an exacerbation-free interval. METHODS: Twenty four patients delta F508 homozygous (median age 20.5 y,...
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