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Article

TGF-beta(1) genotype and accelerated decline in lung function of patients with cystic fibrosis.

Thorax - 1 Jun 2000

Arkwright P D, Laurie S, Super M, Pravica V, Schwarz M J, Webb A K, Hutchinson I V

Abstract excerpt

BACKGROUND: Polymorphisms in transforming growth factor (TGF)-beta(1) associated with variations in cytokine levels are linked to fibrosis in a number of tissues. However, the contribution of this cytokine to organ fibrosis in patients with cystic fibrosis is presently unclear. This study was undertaken to examine the association between TGF-beta(1) gene polymorphisms and the development of pulmonary dysfunction...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Forced Expiratory Volume

Share to Polymorphism, Genetic

Share to Respiratory Insufficiency

Share to Transforming Growth Factor beta

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Source

Open in PubMed Open full text

Identifiers

PMID: 10817792
DOI: 10.1136/thorax.55.6.459
PMCID: PMC1745768

Genes

CFTR
FEV

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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