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Article

Polymorphisms of TGF-beta1 in cystic fibrosis patients.

Clinical immunology (Orlando, Fla.) - 1 Dec 2006

Brazova Jitka, Sismova Kristyna, Vavrova Vera, Bartosova Jana, Macek Milan, Lauschman Hynek, Sediva Anna

Abstract excerpt

There is a significant phenotypic variance among cystic fibrosis (CF) patients. Due to the role of TGF-beta1 in fibrotic processes we investigated its role in CF pathogenesis. TGF-beta 1 codons 10 and 25 were genotyped in 118 Czech CF patients and 268 controls by PCR-ARMS. Difference between CF and controls was found at codon 10, lower frequency of T/T homozygotes, and codon 25, higher frequency of G/C...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17052957
DOI: 10.1016/j.clim.2006.08.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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