Article

The Effect of TGF-β1 Polymorphisms on Pulmonary Disease Progression in Patients with Cystic Fibrosis

2021-06-29

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: Transforming Growth Factor-β<sub>1</sub> (TGF-β<sub>1</sub>) is a genetic modifier in patients with cystic fibrosis (CF). Several single nucleotide polymorphisms (SNPs) of TGF-β<sub>1</sub> are associated with neutrophilic inflammation, lung fibrosis und loss of pulmonary function.<bold>Aim</bold>: The aim of this study was to assess the relationship between gen...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 726c43d7-c9f7-51aa-9ecb-3e71d19d0504
DOI: 10.21203/rs.3.rs-644306/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The Effect of TGF-β1 Polymorphisms on Pulmonary Disease Progression in Patients with Cystic FibrosisDOI 10.21203/rs.3.rs-644306/v1Read

The effect of TGF-β1 polymorphisms on pulmonary disease progression in patients with cystic fibrosis.Semantic proximity Read

The effect of TGF-beta1 polymorphisms on pulmonary disease progression in patients with cystic fibrosisSemantic proximity Read

Association of Serum TGF-β1 Levels with Different Clinical Phenotypes of Cystic Fibrosis Exacerbation.Semantic proximity Read

Genetic variations in inflammatory mediators influence lung disease progression in cystic fibrosis.Semantic proximity Read

Cytokine gene polymorphisms and severity of CF lung disease.Semantic proximity Read

TGF-beta(1) genotype and accelerated decline in lung function of patients with cystic fibrosis.Semantic proximity Read

Transforming growth factor β1 genotypes in relation to TGFβ1, interleukin-8, and tumor necrosis factor alpha in induced sputum and blood in cystic fibrosis.Semantic proximity Read

Plasma TGF-β₁ in pediatric cystic fibrosis: potential biomarker of lung disease and response to therapy.Semantic proximity Read

IL1B gene variants, but not TNF, CXCL8, IL6 and IL10, modify the course of cystic fibrosis in Polish patients.Semantic proximity Read

Role of the TGF-β cytokine and its gene polymorphisms in asthma etiopathogenesisSemantic proximity Read

Genetic modifiers of lung disease in cystic fibrosis.Semantic proximity Read

Ancestral haplotype 8.1 and lung disease severity in European cystic fibrosis patients.Semantic proximity Read