Article
Elevated plasma TGF-beta1 levels in patients with chronic obstructive pulmonary disease.
Respiratory medicine - 1 Jul 2009
Mak Judith C W, Chan-Yeung Moira M W, Ho Siu P, Chan Kin S, Choo Kahlin, Yee Kwok S, Chau Chi H, Cheung Amy H K, Ip Mary S M
Abstract excerpt
BACKGROUND: Transforming growth factor-beta(1) (TGF-beta(1)), a multifunctional cytokine, has been implicated to be responsible for the increased deposition of extracellular matrix in the airways, and increased submucosal collagen expression in chronic obstructive pulmonary disease (COPD). We determined plasma TGF-beta(1) levels in patients with COPD and explored its association with common functional...
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