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Article

Effects of mutations in the repA gene of plasmid Rts1 on plasmid replication and autorepressor function.

Journal of bacteriology - 1 Feb 1990

Terawaki Y, Nozue H, Zeng H, Hayashi T, Kamio Y, Itoh Y

Abstract excerpt

We constructed a system in which wild-type RepA or RepAcop1 protein was supplied in trans in various amounts to coexisting mini-Rts1 plasmids by clones of the repA or repAcop1 gene under the control of the native promoter with or without its operator sequence. RepAcop1 protein which contains a single amino acid substitution (Arg-142 to Lys) within its 288 amino acids could initiate the replication of the...

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Source

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Identifiers

PMID: 2404957
DOI: 10.1128/jb.172.2.786-792.1990
PMCID: PMC208507

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Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Effects of mutations in the repA gene of plasmid Rts1 on plasmid replication and autorepressor function.PMID 2404957Read ↗

Site-directed mutations in the repA C-terminal region of plasmid Rts1: pleiotropic effects on the replication and autorepressor functions.Semantic proximity Read ↗

Function of the N-terminal half of RepA in activation of Rts1 ori.Semantic proximity Read ↗

Location of a P1 plasmid replication inhibitor determinant within the initiator gene.Semantic proximity Read ↗

Control of replication of plasmid R1: the intergenic region between copA and repA modulates the level of expression of repA.Semantic proximity Read ↗

DnaA dependent replication of plasmid R1 occurs in the presence of point mutations that disrupt the dnaA box of oriR.Semantic proximity Read ↗

Mutations of DnaA-boxes in the oriR region increase replication frequency of the MiniR1-1 plasmid.Semantic proximity Read ↗

Regulation of replication of plasmid R1: an analysis of the intergenic region between copA and repA.Semantic proximity Read ↗

Mutations in an antisense RNA, involved in the replication control of a repABC plasmid, that disrupt plasmid incompatibility and mediate plasmid speciation.Semantic proximity Read ↗

In vivo and in vitro studies of a copy number mutation of the RepA replication protein of plasmid pSC101.Semantic proximity Read ↗

Participation of the Escherichia coli heat shock proteins DnaJ, DnaK, and GrpE in autorepression of the P1 plasmid repA promoter.Semantic proximity Read ↗

Effect of CIS on activity in trans of the replication initiator protein of an IncB plasmid.Semantic proximity Read ↗

Modulation of pPS10 host range by plasmid-encoded RepA initiator protein.Semantic proximity Read ↗

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