Article
Regulation of replication of plasmid R1: an analysis of the intergenic region between copA and repA.
Molecular & general genetics : MGG - 1 Nov 1991
Ohman M, Wagner E G
Abstract excerpt
The synthesis of the rate-limiting RepA replication initiator protein of plasmid R1 is negatively controlled by an antisense RNA, CopA. The regulation is posttranscriptional and involves an inhibitory effect on RepA translation mediated by the binding of CopA to its target (CopT) in the leader re...
Topics
- Bacterial Proteins
- Base Sequence
- Blotting, Northern
- DNA Helicases
- DNA Replication
- DNA, Bacterial
- DNA-Binding Proteins
- Escherichia coli
- Genes, Bacterial
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Mutation
- Nucleic Acid Conformation
- Plasmids
- Protein Biosynthesis
- Proteins
- RNA Processing, Post-Transcriptional
- RNA, Antisense