Article
Participation of the Escherichia coli heat shock proteins DnaJ, DnaK, and GrpE in autorepression of the P1 plasmid repA promoter.
The New biologist - 1 Sept 1990
Tilly K, Sozhamannan S, Yarmolinsky M
Abstract excerpt
The replicon of the low copy number plasmid P1 uses the three Escherichia coli heat shock proteins DnaJ, DnaK, and GrpE for the efficient initiation of its DNA replication. The only P1-encoded protein required for plasmid replication is the initiator, RepA. Binding of RepA to the origin also repr...
Topics
- Bacterial Proteins
- DNA Helicases
- DNA Replication
- DNA-Binding Proteins
- Escherichia coli
- Genes, Regulator
- Genetic Complementation Test
- Heat-Shock Proteins
- Mutation
- Plasmids
- Promoter Regions, Genetic
- Proteins
- Trans-Activators
