Article
Single nucleotide polymorphisms in the D-loop region of mitochondrial DNA is associated with renal cell carcinoma outcome.
Mitochondrial DNA - 1 Apr 2015
Bai Yaling, Guo Zhanjun, Xu Jinsheng, Liu Shufeng, Zhang Junxia, Cui Liwen, Zhang Huiran, Zhang Shenglei
Abstract excerpt
Accumulation of single nucleotide polymorphisms (SNPs) in the displacement loop (D-loop) of mitochondrial DNA (mtDNA) has been described in various types of cancers and might be associated with cancer risk and disease outcome. We identified 14 SNPs with a frequency higher than 5% and 5 SNPs associated with the risk of renal cell carcinoma (RCC) in a case-control study previously. In the present study, we assessed...
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