Article
Sequence polymorphisms of mitochondrial D-loop and hepatocellular carcinoma outcome.
Biochemical and biophysical research communications - 18 Mar 2011
Wang Cuiju, Zhang Fengbin, Fan Haiyan, Peng Li, Zhang Ruixing, Liu Shufeng, Guo Zhanjun
Abstract excerpt
Accumulation of mutations and single nucleotide polymorphisms (SNPs) in the displacement loop (D-loop) of mitochondrial DNA (mtDNA) might be associated with cancer risk and disease outcome. We investigated the prediction power of D-loop SNPs in hepatocellular carcinoma (HCC) patients. No mutation in these HCC patients has prediction power for post-operational survival, whereas two SNP sites (nucleotides 146 T/C...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
