Article
Single nucleotide polymorphisms in the mitochondrial displacement loop and outcome of esophageal squamous cell carcinoma.
Journal of experimental & clinical cancer research : CR - 26 Nov 2010
Zhang Ruixing, Wang Rui, Zhang Fengbin, Wu Chensi, Fan Haiyan, Li Yan, Wang Cuiju, Guo Zhanjun
Abstract excerpt
BACKGROUND: Accumulation of single nucleotide polymorphisms (SNPs) in the displacement loop (D-loop) of mitochondrial DNA (mtDNA) has been described for different types of cancers and might be associated with cancer risk and disease outcome. We used a population-based series of esophageal squamous cell carcinoma (ESCC) patients for investigating the prediction power of SNPs in mitochondrial D-loop. METHODS: The...
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