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Article

D-loop Mutations in Renal Cell Carcinoma Improve Predictive Accuracy for Cancer-Related Death by Integrating with Mutations in the NADH Dehydrogenase Subunit 1 Gene.

Genes - 2 Dec 2019

Kim Hakushi, Komiyama Tomoyoshi, Nitta Masahiro, Kawamura Yoshiaki, Hasegawa Masanori, Shoji Sunao, Orihashi Yasushi, Inomoto Chie, Kajiwara Hiroshi, Nakamura Naoya, Kobayashi Hiroyuki, Miyajima Akira

Abstract excerpt

Renal cell carcinoma (RCC) is associated with various genetic alterations. Although whole-genome/exome sequencing analysis has revealed that nuclear genome alterations are associated with clinical outcomes, the association between nucleotide alterations in the mitochondrial genome and RCC clinical outcomes remains unclear. In this study, we analyzed somatic mutations in the mitochondrial D-loop region, using RCC...

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Identifiers

PMID: 31810328
DOI: 10.3390/genes10120998
PMCID: PMC6947453

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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