Article
Single nucleotide polymorphisms in the D-loop region of mitochondrial DNA are associated with epithelial ovarian cancer prognosis.
Mitochondrial DNA - 1 Jan 2015
Kong Desheng, Shi Shuhong, Li Yanfang
Abstract excerpt
OBJECTIVE: The single nucleotide polymorphisms (SNPs) in the displacement loop (D-loop) of mitochondrial DNA (mtDNA) is found in many types of cancers. A lot of reports show the SNPs of D-loop may be related to cancers prognosis. This study investigated whether the SNPs were associated with the outcome of epithelial ovarian cancer (EOC). METHOD: The D-loop region of mtDNA samples from blood were obtained from 89...
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