Article
Single nucleotide polymorphisms in the mitochondrial displacement loop region predict malignant melanoma outcome: a study in Chinese Han population.
Mitochondrial DNA. Part A, DNA mapping, sequencing, and analysis - 1 May 2016
Li Zhenxing, Deng Binbin, Wang Wei, Jia Zhifeng, Liu Xujian, Li Ning
Abstract excerpt
BACKGROUND: Accumulation of single nucleotide polymorphisms (SNPs) in the displacement loop (D-loop) of mitochondrial DNA (mtDNA) has been identified to be associated with cancer risk and disease outcome. In this study, we investigated whether the SNPs in mitochondrial D-loop were associated with the outcome of malignant melanoma (MM) in Chinese Han population. METHODS: The D-loop region of mtDNA was sequenced...
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