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Article

Pre- and postsynaptic modulations of hypoglossal motoneurons by α-adrenoceptor activation in wild-type and Mecp2(-/Y) mice.

American journal of physiology. Cell physiology - 15 Nov 2013

Jin Xiao-Tao, Cui Ningren, Zhong Weiwei, Jin Xin, Wu Zhongying, Jiang Chun

Abstract excerpt

Hypoglossal motoneurons (HNs) control tongue movement and play a role in maintenance of upper airway patency. Defects in these neurons may contribute to the development of sleep apnea and other cranial motor disorders including Rett syndrome (RTT). HNs are modulated by norepinephrine (NE) through α-adrenoceptors. Although postsynaptic mechanisms are known to play a role in this effect, how NE modulates the...

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Identifiers

PMID: 23986203
DOI: 10.1152/ajpcell.00109.2013
PMCID: PMC3840201

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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