Article

Serotonin therapies for opioid-induced dysphagia and respiratory depression: sex differences in a rat electromyography model

2023-08-22

Abstract excerpt

Opioids are well-known to cause respiratory depression, but despite clinical evidence of dysphagia, the effects of opioids on swallow excitability and motor pattern are unknown. We sought to test the effects of the clinically-relevant opioid buprenorphine on pharyngeal swallow and respiratory drive in male and female rats. We also evaluated utility of serotonin 5-HT1A agonists (8-OH-DPAT and buspirone) to improve...

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Literature Corpus work: fb1ecc20-cb29-5458-b187-1c35dbbe7002
DOI: 10.1101/2023.08.21.554164

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Serotonin therapies for opioid-induced dysphagia and respiratory depression: sex differences in a rat electromyography modelDOI 10.1101/2023.08.21.554164Read

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