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Article

Enhanced dense core granule function and adrenal hypersecretion in a mouse model of Rett syndrome.

The European journal of neuroscience - 1 Aug 2009

Ladas Thomas, Chan Shyue-An, Ogier Michael, Smith Corey, Katz David M

Abstract excerpt

Rett syndrome (RTT) is a progressive developmental disorder resulting from loss-of-function mutations in the gene encoding methyl-CpG-binding protein 2 (MeCP2), a transcription regulatory protein. The RTT phenotype is complex and includes severe cardiorespiratory abnormalities, dysautonomia and behavioral symptoms of elevated stress. These findings have been attributed to an apparent hyperactivity of the...

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Identifiers

PMID: 19674087
DOI: 10.1111/j.1460-9568.2009.06858.x
PMCID: PMC2758854

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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