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Article

CD33 in Alzheimer's disease.

Molecular neurobiology - 1 Feb 2014

Jiang Teng, Yu Jin-Tai, Hu Nan, Tan Meng-Shan, Zhu Xi-Chen, Tan Lan

Abstract excerpt

The amyloid-beta peptide (Aβ) cascade hypothesis posits that Aβ accumulation is the fundamental initiator of Alzheimer's disease (AD), and mounting evidence suggests that impaired Aβ clearance rather than its overproduction is the major pathogenic event for AD. Recent genetic studies have identified cluster of differentiation 33 (CD33) as a strong genetic locus linked to AD. As a type I transmembrane protein,...

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Identifiers

PMID: 23982747
DOI: 10.1007/s12035-013-8536-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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