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Article

Wnt-related genes and large-joint osteoarthritis: association study and replication.

Rheumatology international - 1 Nov 2013

García-Ibarbia Carmen, Pérez-Castrillón José L, Ortiz Fernando, Velasco Javier, Zarrabeitia María T, Sumillera Manuel, Riancho José A

Abstract excerpt

Osteoarthritis (OA) has a strong genetic component, and experimental evidence suggests the involvement of the Wnt pathway in its pathogenesis. Hence, we explored the association of common single nucleotide polymorphisms (SNPs) related to the Wnt pathway with hip and knee OA. Seventy-eight SNPs were analyzed in 606 patients undergoing joint replacement and in 680 control subjects. SNPs were located in WNT1,...

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Source

Identifiers

PMID: 23864140
DOI: 10.1007/s00296-013-2821-1

Genes

BCL9
SFRP4
DVL2
FZD5
SFRP1
WNT1
WNT16

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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