Article
Single Nucleotide Polymorphisms and Osteoarthritis: An Overview and a Meta-Analysis.
Medicine - 1 Feb 2016
Wang Ting, Liang Yuting, Li Hong, Li Haibo, He Quanze, Xue Ying, Shen Cong, Zhang Chunhua, Xiang Jingjing, Ding Jie, Qiao Longwei, Zheng Qiping
Abstract excerpt
Osteoarthritis (OA) is a complex disorder characterized by degenerative articular cartilage and is largely attributed to genetic risk factors. Single nucleotide polymorphisms (SNPs) are common DNA variants that have shown promising and efficiency, compared with positional cloning, to map candidate genes of complex diseases, including OA. In this study, we aim to provide an overview of multiple SNPs from a number...
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