Article
Wnt pathway genes in osteoporosis and osteoarthritis: differential expression and genetic association study.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA - 1 Jan 2010
Velasco J, Zarrabeitia M T, Prieto J R, Perez-Castrillon J L, Perez-Aguilar M D, Perez-Nuñez M I, Sañudo C, Hernandez-Elena J, Calvo I, Ortiz F, Gonzalez-Macias J, Riancho J A
Abstract excerpt
UNLABELLED: In comparison with hip fractures, increased expression of genes in the Wnt pathway and increased Wnt activity were found in bone samples and osteoblast cultures from patients with osteoarthritis, suggesting the involvement of this pathway in subchondral bone changes. No consistent differences were found in the genetic association study. INTRODUCTION: This study aims to explore the allelic variations...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.