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Article

Interleukin-17 and Toll-like Receptor 10 genetic polymorphisms and susceptibility to large joint osteoarthritis.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society - 1 Jun 2018

Vrgoc Goran, Vrbanec Jurica, Eftedal Randi K, Dembic Petra L, Balen Sanja, Dembic Zlatko, Jotanovic Zdravko

Abstract excerpt

Primary osteoarthritis (OA) is the most common type of a joint disease. It has a polygenic risk inheritance pattern and affects older people. The etiology of this disease is not fully understood. The aim of this study was to investigate the associations between polymorphisms in pro-inflammatory interleukin-17 (IL17A and IL17F) and anti-inflammatory Toll-like Receptor 10 (TLR10) genes with the risk for development...

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Source

Identifiers

PMID: 29194748
DOI: 10.1002/jor.23823

Genes

TLR10

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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