Genetic epidemiology of hip and knee osteoarthritis.

Abstract excerpt

Osteoarthritis (OA) is the most common cause of arthritis and represents an enormous healthcare burden in industrialized societies. Current therapeutic approaches for OA are limited and are insufficient to prevent the initiation and progression of the disease. Genetic studies of patients with OA can help to unravel the molecular mechanisms responsible for specific disease manifestations, including joint damage,...

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• Collagen Type VI
• Genetic Predisposition to Disease
• Growth Differentiation Factor 5
• Osteoarthritis, Hip
• Osteoarthritis, Knee