A genome-wide supported variant in CACNA1C influences hippocampal activation during episodic memory encoding and retrieval.

doi:10.1007/s00406-013-0428-x

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Article

A genome-wide supported variant in CACNA1C influences hippocampal activation during episodic memory encoding and retrieval.

European archives of psychiatry and clinical neuroscience - 1 Mar 2014

Krug Axel, Witt Stephanie H, Backes Heidelore, Dietsche Bruno, Nieratschker Vanessa, Shah N Jon, Nöthen Markus M, Rietschel Marcella, Kircher Tilo

Abstract excerpt

The alpha 1C subunit of the L-type voltage-gated calcium channel (CACNA1C) gene is one of the best replicated susceptibility loci for bipolar disorder, schizophrenia and major depression. It is involved in learning, memory and brain plasticity. Genetic studies using functional magnetic resonance imaging (fMRI) reported evidence of association with the CACNA1C single nucleotide polymorphism rs1006737 with...

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PMID: 23860750
DOI: 10.1007/s00406-013-0428-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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