Replication of brain function effects of a genome-wide supported psychiatric risk variant in the CACNA1C gene and new multi-locus effects.

doi:10.1016/j.neuroimage.2014.03.007

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Article

Replication of brain function effects of a genome-wide supported psychiatric risk variant in the CACNA1C gene and new multi-locus effects.

NeuroImage - 1 Jul 2014

Erk Susanne, Meyer-Lindenberg Andreas, Linden David E J, Lancaster Thomas, Mohnke Sebastian, Grimm Oliver, Degenhardt Franziska, Holmans Peter, Pocklington Andrew, Schmierer Phöbe, Haddad Leila, Mühleisen Thomas W, Mattheisen Manuel, Witt Stephanie H, Romanczuk-Seiferth Nina, Tost Heike, Schott Björn H, Cichon Sven, Nöthen Markus M, Rietschel Marcella, Heinz Andreas, Walter Henrik

Abstract excerpt

Variation in the CACNA1C gene has consistently been associated with psychosis in genome wide association studies. We have previously shown in a sample of n=110 healthy subjects that carriers of the CACNA1C rs1006737 risk variant exhibit hippocampal and perigenual anterior cingulate dysfunction (pgACC) during episodic memory recall. Here, we aimed to replicate our results, by testing for the effects of the...

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PMID: 24642287
DOI: 10.1016/j.neuroimage.2014.03.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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