Article
CACNA1C risk variant and amygdala activity in bipolar disorder, schizophrenia and healthy controls.
PloS one - 1 Jan 2013
Tesli Martin, Skatun Kristina C, Ousdal Olga Therese, Brown Andrew Anand, Thoresen Christian, Agartz Ingrid, Melle Ingrid, Djurovic Srdjan, Jensen Jimmy, Andreassen Ole A
Abstract excerpt
OBJECTIVES: Several genetic studies have implicated the CACNA1C SNP rs1006737 in bipolar disorder (BD) and schizophrenia (SZ) pathology. This polymorphism was recently found associated with increased amygdala activity in healthy controls and patients with BD. We performed a functional Magnetic Resonance Imaging (fMRI) study in a sample of BD and SZ cases and healthy controls to test for altered amygdala activity...
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