Association of a CAMK2A genetic variant with logical memory performance and hippocampal volume in the elderly.

doi:10.1016/j.brainresbull.2020.05.001

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Article

Association of a CAMK2A genetic variant with logical memory performance and hippocampal volume in the elderly.

Brain research bulletin - 1 Aug 2020

Rhein Cosima, Mühle Christiane, Lenz Bernd, Richter-Schmidinger Tanja, Kogias Georgios, Boix Fernando, Lourdusamy Anbarasu, Dörfler Arnd, Peters Oliver, Ramirez Alfredo, Jessen Frank, Maier Wolfgang, Hüll Michael, Frölich Lutz, Teipel Stefan, Wiltfang Jens, Kornhuber Johannes, Müller Christian P

Abstract excerpt

Calcium/Calmodulin-dependent kinase alpha (αCaMKII) has been shown to play an essential role in synaptic plasticity and in learning and memory in animal models. However, there is little evidence for an involvement in specific memories in humans. Here we tested the potential involvement of the αCaMKII coding gene CAMK2A in verbal logical memory in two Caucasian populations from Germany, in a sample of 209 elderly...

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PMID: 32418901
DOI: 10.1016/j.brainresbull.2020.05.001

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