Article
Effect of CACNA1C rs1006737 on neural correlates of verbal fluency in healthy individuals.
NeuroImage - 15 Jan 2010
Krug Axel, Nieratschker Vanessa, Markov Valentin, Krach Sören, Jansen Andreas, Zerres Klaus, Eggermann Thomas, Stöcker Tony, Shah N Jon, Treutlein Jens, Mühleisen Thomas W, Kircher Tilo
Abstract excerpt
BACKGROUND: Recent genetic studies found the A allele of the variant rs1006737 in the alpha 1C subunit of the L-type voltage-gated calcium channel (CACNA1C) gene to be overrepresented in patients suffering from bipolar disorder, schizophrenia or major depression. While the functions underlying the pathophysiology of these psychiatric disorders are yet unknown, impaired performance in verbal fluency tasks is an...
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