Article
Effects of a CACNA1C genotype on attention networks in healthy individuals.
Psychological medicine - 1 Jul 2011
Thimm M, Kircher T, Kellermann T, Markov V, Krach S, Jansen A, Zerres K, Eggermann T, Stöcker T, Shah N J, Nöthen M M, Rietschel M, Witt S H, Mathiak K, Krug A
Abstract excerpt
BACKGROUND: Recent genetic studies found the A allele of the variant rs1006737 in the alpha 1C subunit of the L-type voltage-gated calcium channel (CACNA1C) gene to be over-represented in patients with psychosis, including schizophrenia, bipolar disorder and major depressive disorder. In these disorders, attention deficits are among the main cognitive symptoms and have been related to altered neural activity in...
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