Article
Substantial effects of apolipoprotein E ε4 on memory decline in very old age: longitudinal findings from a population-based sample.
Neurobiology of aging - 1 Dec 2013
Praetorius Marcus, Thorvaldsson Valgeir, Hassing Linda B, Johansson Boo
Abstract excerpt
We examined associations between the apolipoprotein E (APOE) ε4 allele and levels of performance and rates of change in cognition in late life taking incident dementia into account. The sample consisted of 482 nondemented individuals, aged 80 years and older at baseline, drawn from the OCTO twin study. A battery of 10 cognitive tests was administered at 5 occasions with measurements intervals of 2 years. We...
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