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Article

Sex differences in the association of the apolipoprotein E epsilon 4 allele with incidence of dementia, cognitive impairment, and decline.

Neurobiology of aging - 1 Apr 2012

Beydoun May A, Boueiz Adel, Abougergi Marwan S, Kitner-Triolo Melissa H, Beydoun Hind A, Resnick Susan M, O'Brien Richard, Zonderman Alan B

Abstract excerpt

We examined longitudinal associations between the apolipoprotein E ε4 allele (ApoE4(+) status) and several cognitive outcomes and tested effect modification by sex. Data on 644 non-Hispanic Caucasian adults, from the Baltimore Longitudinal Study of Aging (BLSA) were used. Dementia onset, cognitive impairment and decline were assessed longitudinally. After 27.5 years median follow-up, 113 participants developed...

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Identifiers

PMID: 20619505
DOI: 10.1016/j.neurobiolaging.2010.05.017
PMCID: PMC2974952

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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