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Article

Apolipoprotein E ε4 and later-life decline in cognitive function and grip strength.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry - 1 Oct 2013

Batterham Philip J, Bunce David, Cherbuin Nicolas, Christensen Helen

Abstract excerpt

OBJECTIVES: Presence of the apolipoprotein E (APOE) ε4 allele is a risk factor for dementia, whereas the ε2 allele offers protection against dementia. There is also evidence for a relationship between APOE genotype and changes in cognitive function. It is not clear, however, whether this relationship stems from undetected disease in persons genetically more vulnerable to dementia. This study examined whether APOE...

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Identifiers

PMID: 23567378
DOI: 10.1016/j.jagp.2013.01.035

Genes

APOE

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