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Article

Experimental analysis of co-evolution within protein complexes: the yeast exosome as a model.

Proteins - 1 Nov 2013

Sandler Inga, Medalia Ohad, Aharoni Amir

Abstract excerpt

Extensive bioinformatics analysis suggests that the stability and function of protein complexes are maintained throughout evolution by coordinated changes (co-evolution) of complex subunits. Yet, relatively little is known regarding the actual dynamics of such processes and the functional implications of co-evolution within protein complexes, since most of the bioinformatics predictions were not analyzed...

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PMID: 23852635
DOI: 10.1002/prot.24360

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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