Article
System-wide analyses of the fission yeast poly(A)+ RNA interactome reveal insights into organization and function of RNA-protein complexes.
Genome research - 1 Jul 2020
Kilchert Cornelia, Kecman Tea, Priest Emily, Hester Svenja, Aydin Ebru, Kus Krzysztof, Rossbach Oliver, Castello Alfredo, Mohammed Shabaz, Vasiljeva Lidia
Abstract excerpt
Large RNA-binding complexes play a central role in gene expression and orchestrate production, function, and turnover of mRNAs. The accuracy and dynamics of RNA-protein interactions within these molecular machines are essential for their function and are mediated by RNA-binding proteins (RBPs). Here, we show that fission yeast whole-cell poly(A)+ RNA-protein crosslinking data provide information on the...
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