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Article

Evolutionary Conservation and Diversification of Puf RNA Binding Proteins and Their mRNA Targets.

PLoS biology - 1 Jan 2015

Hogan Gregory J, Brown Patrick O, Herschlag Daniel

Abstract excerpt

Reprogramming of a gene's expression pattern by acquisition and loss of sequences recognized by specific regulatory RNA binding proteins may be a major mechanism in the evolution of biological regulatory programs. We identified that RNA targets of Puf3 orthologs have been conserved over 100-500 million years of evolution in five eukaryotic lineages. Focusing on Puf proteins and their targets across 80 fungi, we...

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Identifiers

PMID: 26587879
DOI: 10.1371/journal.pbio.1002307
PMCID: PMC4654594

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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