Article
TGFβ1 Polymorphisms Predict Distant Metastasis-Free Survival in Patients with Inoperable Non-Small-Cell Lung Cancer after Definitive Radiotherapy.
PloS one - 1 Jan 2013
Yuan Xianglin, Wei Qingyi, Komaki Ritsuko, Liu Zhensheng, Yang Ju, Tucker Susan L, Xu Ting, Heymach John V, Lu Charles, Cox James D, Liao Zhongxing
Abstract excerpt
PURPOSE: Transforming growth factor (TGF) -β1 signaling is involved in cancer-cell metastasis. We investigated whether single nucleotide polymorphisms (SNPs) at TGFβ1 were associated with overall survival (OS) and distant metastasis-free survival (DMFS) in patients with non-small cell lung cancer (NSCLC) treated with definitive radiotherapy, with or without chemotherapy. METHODS: We genotyped TGFβ1 SNPs at...
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