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Article

Nomograms incorporating genetic variants in BMP/Smad4/Hamp pathway to predict disease outcomes after definitive radiotherapy for non-small cell lung cancer.

Cancer medicine - 1 Jun 2018

Yang Ju, Xu Ting, Gomez Daniel R, Yuan Xianglin, Nguyen Quynh-Nhu, Jeter Melenda, Song Yipeng, Komaki Ritsuko, Hu Ye, Hahn Stephen M, Liao Zhongxing

Abstract excerpt

Hepcidin is crucial in regulating iron metabolism, and increased serum levels were strongly linked with poor outcomes in various malignancies. Thus, we investigated if genetic variants in the BMP/Smad4/Hamp hepcidin-regulating pathway were associated with outcomes in patients receiving definitive radiotherapy for NSCLC. Subjects were 664 NSCLC patients who received ≥60 Gy radiotherapy for NSCLC retrospectively...

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Share to Bone Morphogenetic Protein 2
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29745043
DOI: 10.1002/cam4.1349
PMCID: PMC6010922

Genes

BMP2
BMP4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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