Article
TNFRSF1B +676 T>G polymorphism predicts survival of non-small cell lung cancer patients treated with chemoradiotherapy.
BMC cancer - 14 Oct 2011
Guan Xiaoxiang, Liao Zhongxin, Ma Hongxia, Qian Ji, Liu Zhensheng, Yuan Xianglin, Gomez Daniel, Komaki Ritsuko, Wang Li-E, Wei Qingyi
Abstract excerpt
BACKGROUND: The dysregulation of gene expression in the TNF-TNFR superfamily has been involved in various human cancers including non-small cell lung cancer (NSCLC). Furthermore, functional polymorphisms in TNF-α and TNFRSF1B genes that alter gene expression are likely to be associated with risk and clinical outcomes of cancers. However, few reported studies have investigated the association between potentially...
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