Article
Association between single nucleotide polymorphisms of the transforming growth factor-β1 gene and overall survival in unresectable locally advanced non-small-cell lung cancer patients treated with radio(chemo)therapy in a Chinese population.
Medical oncology (Northwood, London, England) - 1 Jun 2013
Xue Sheng-Liu, Zheng Yi-Hu, Su Hua-Fang, Deng Xia, Zhang Xue-Bang, Zou Chang-Lin, Hu Mei-Long, Xie Cong-Ying
Abstract excerpt
The outcome is variable for unresectable locally advanced non-small-cell lung cancer (ULANSCLC) patients treated with radio(chemo)therapy. The aim of this study is to investigate whether single-nucleotide polymorphisms (SNPs) in the transforming growth factor-beta1 (TGF-β1) gene are associated with overall survival (OS) in ULANSCLC patients treated with definitive radio(chemo)therapy. A total of 109 patients who...
Topics
- Adult
- Aged
- Asian People
- Biomarkers, Tumor
- Carcinoma, Non-Small-Cell Lung
- Chemoradiotherapy
- Cohort Studies
- Female
- Genetic Association Studies