Single nucleotide polymorphism at rs1982073:T869C of the TGFbeta 1 gene is associated with the risk of radiation pneumonitis in patients with non-small-cell lung cancer treated with definitive radiotherapy.

doi:10.1200/JCO.2008.20.6763

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Article

Single nucleotide polymorphism at rs1982073:T869C of the TGFbeta 1 gene is associated with the risk of radiation pneumonitis in patients with non-small-cell lung cancer treated with definitive radiotherapy.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 10 Jul 2009

Yuan Xianglin, Liao Zhongxing, Liu Zhensheng, Wang Li-E, Tucker Susan L, Mao Li, Wang Xin Shelley, Martel Mary, Komaki Ritsuko, Cox James D, Milas Luka, Wei Qingyi

Abstract excerpt

PURPOSE: In search of reliable biologic markers to predict the risk of normal tissue damage by radio(chemo)therapy before treatment, we investigated the association between single nucleotide polymorphisms (SNPs) in the transforming growth factor 1 (TGFbeta1) gene and risk of radiation pneumonitis (RP) in patients with non-small-cell lung cancer (NSCLC). PATIENTS AND METHODS: Using 164 available genomic DNA...

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Identifiers

PMID: 19380441
DOI: 10.1200/JCO.2008.20.6763
PMCID: PMC4385796

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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