Article
A study of ethnic differences in TGFβ1 gene polymorphisms and effects on the risk of radiation pneumonitis in non-small-cell lung cancer.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Nov 2012
Niu Xiaomin, Li Hongxuan, Chen Zhiwei, Liu Yun, Kan Mengyuan, Zhou Daizhan, Li Ziming, Ye Xiangyun, Shen Shengping, Lv Changxing, Lu Shun
Abstract excerpt
BACKGROUND: To investigate whether Chinese non-small-cell lung cancer (NSCLC) patients with risk of radiation pneumonitis (RP) (grade ≥ 3) caused by radiotherapy display reliable single-nucleotide polymorphism (SNP) marker(s) located on the transforming growth factor-beta-1 (TGFβ1) gene. METHODS: DNA was isolated from blood samples obtained from NSCLC patients (n = 167) treated with radiotherapy alone (n = 23) or...
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