Article
Association between single nucleotide polymorphisms of the transforming growth factor β1 gene and the risk of severe radiation esophagitis in patients with lung cancer.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology - 1 Dec 2012
Guerra Jose Luis Lopez, Gomez Daniel, Wei Qingyi, Liu Zhengshen, Wang Li-E, Yuan Xianglin, Zhuang Yan, Komaki Ritusko, Liao Zhongxing
Abstract excerpt
PURPOSE: We investigated the association between single nucleotide polymorphisms (SNPs) in the transforming growth factor β1 (TGFβ1) gene and the risk of radiation-induced esophageal toxicity (RE) in patients with non-small-cell lung cancer (NSCLC). METHODS AND MATERIALS: Ninety-seven NSCLC patients with available genomic DNA samples and mostly treated with intensity modulated radio(chemo)therapy from 2003 to...
Topics
- Analysis of Variance
- Carcinoma, Non-Small-Cell Lung
- Chemotherapy, Adjuvant
- Esophagitis
- Female
- Genetic Markers
- Genotype
- Humans
- Lung Neoplasms
- Male
- Middle Aged
- Multivariate Analysis