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Article

Genetic variations in the transforming growth factor-beta pathway as predictors of survival in advanced non-small cell lung cancer.

Carcinogenesis - 1 Jul 2011

Lin Moubin, Stewart David J, Spitz Margaret R, Hildebrandt Michelle A T, Lu Charles, Lin Jie, Gu Jian, Huang Maosheng, Lippman Scott M, Wu Xifeng

Abstract excerpt

The magnitude of benefit is variable for advanced non-small cell lung cancer (NSCLC) patients receiving platinum-based chemotherapy. The purpose of this study is to determine whether genetic variations in the transforming growth factor-beta (TGF-β) pathway are associated with clinical outcomes in NSCLC patients receiving first-line platinum-based chemotherapy. Five hundred and ninety-eight advanced-stage NSCLC...

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Source

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Identifiers

PMID: 21515830
DOI: 10.1093/carcin/bgr067
PMCID: PMC3128559

Genes

BMP2
SMAD3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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