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Article

ZO-1 recruitment to α-catenin--a novel mechanism for coupling the assembly of tight junctions to adherens junctions.

Journal of cell science - 1 Sept 2013

Maiers Jessica L, Peng Xiao, Fanning Alan S, DeMali Kris A

Abstract excerpt

The formation of a barrier between epithelial cells is a fundamental determinant of cellular homeostasis, protecting underlying cells against pathogens, dehydration and damage. Assembly of the tight junction barrier is dependent upon neighboring epithelial cells binding to one another and forming adherens junctions, but the mechanism for how these processes are linked is poorly understood. Using a knockdown and...

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Source

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Identifiers

PMID: 23813953
DOI: 10.1242/jcs.126565
PMCID: PMC3757330

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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