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Article

The tight junction protein ZO-1 and an interacting transcription factor regulate ErbB-2 expression.

The EMBO journal - 2 May 2000

Balda M S, Matter K

Abstract excerpt

Epithelial tight junctions regulate paracellular diffusion and restrict the intermixing of apical and basolateral plasma membrane components. We now identify a Y-box transcription factor, ZONAB (ZO-1-associated nucleic acid-binding protein), that binds to the SH3 domain of ZO-1, a submembrane protein of tight junctions. ZONAB localizes to the nucleus and at tight junctions, and binds to sequences of specific...

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Source

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Identifiers

PMID: 10790369
DOI: 10.1093/emboj/19.9.2024
PMCID: PMC305688

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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