Aberrant spindle dynamics and cytokinesis in Dictyostelium discoideum cells that lack glycogen synthase kinase 3.

Abstract excerpt

Eukaryotic cell division requires the co-ordinated assembly and disassembly of the mitotic spindle, accurate chromosome segregation and temporal control of cytokinesis to generate two daughter cells. While the absolute details of these processes differ between organisms, there are evolutionarily conserved core components common to all eukaryotic cells, whose identification will reveal the key processes that...

Topics

• Chromosome Segregation
• Cytokinesis
• Dictyostelium
• Glycogen Synthase Kinase 3
• Mutation
• Protein Binding
• Protozoan Proteins
• Spindle Apparatus