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Article

GSK3, a master switch regulating cell-fate specification and tumorigenesis.

Current opinion in genetics & development - 1 Oct 2000

Kim L, Kimmel A R

Abstract excerpt

Until recently, protein kinase GSK3 (glycogen synthase kinase 3), an essential component for cell-fate specification, had been considered a constitutively activated enzyme subject to developmentally regulated inhibition through hierarchical, linear signaling paths. Data from various systems now indicate more complex scenarios involving activating as well as inhibiting circuits, and the differential formation of...

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Identifiers

PMID: 10980428
DOI: 10.1016/s0959-437x(00)00120-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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