Article

Recent advances in understanding the cellular roles of GSK-3

2017-02-20

Abstract excerpt

Glycogen synthase kinase-3 (GSK-3) is a ubiquitously expressed protein kinase that sits at the nexus of multiple signaling pathways. Its deep integration into cellular control circuits is consummate to its implication in diseases ranging from mood disorders to diabetes to neurodegenerative diseases and cancers. The selectivity and insulation of such a promiscuous kinase from unwanted crosstalk between pathways, wh...

Identifiers and source

Literature Corpus work: 61376bf1-d3aa-58dd-802b-a60df129dc5e
DOI: 10.12688/f1000research.10557.1

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