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Article

GSK3 is a multifunctional regulator of Dictyostelium development.

Development (Cambridge, England) - 1 Sept 2004

Schilde Christina, Araki Tsuyoshi, Williams Hazel, Harwood Adrian, Williams Jeffrey G

Abstract excerpt

Glycogen synthase kinase 3 (GSK3) is a central regulator of metazoan development and the Dictyostelium GSK3 homologue, GskA, also controls cellular differentiation. The originally derived gskA-null mutant exhibits a severe pattern formation defect. It forms very large numbers of pre-basal disc cells at the expense of the prespore population. This defect arises early during multicellular development, making it...

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Identifiers

PMID: 15342480
DOI: 10.1242/dev.01330

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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